Mikroenkapsulasi Bisoprolol dengan Penyalut Albumin
نویسندگان
چکیده
Sejalan dengan kemajuan teknologi di bidang farmasi, teknik mikroenkapsulasi telah digunakan untuk memperbaiki stabilitas zat aktif. Tujuan: Penelitian ini bertujuan mengetahui apakah bisoprolol dapat mikrokapsul mengggunakan albumin. Metode: bersifat eksperimental memformulasikan albumin sebagai penyalut yang adalah 1:6, 1:4 dan 1:2 berturut-turut Formula I, II III menggunakan metode penguapan pelarut. Hasil: Albumin mikroenkapasulasi distribusi ukuran partikel 209-1998 µm. Hasil penelitian menunjukkan bahwa perbandingan antara 1:6 memiliki pelepasan aktif paling baik disolusi dari Kesimpulan: dimana semakin besar konsentrasi bahan akan diperlambat.
منابع مشابه
Making bisoprolol a perioperative agent.
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ژورنال
عنوان ژورنال: Jurnal dunia farmasi
سال: 2021
ISSN: ['2548-3560']
DOI: https://doi.org/10.33085/jdf.v5i1.4762